Source:http://linkedlifedata.com/resource/pubmed/id/21168724
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2010-12-20
|
| pubmed:abstractText |
Acute rejection (AR) after kidney transplantation resulting from alloimmune responses has a negative effect on graft survival. AR is mainly caused by T-cell immune responses activated by cytokines, including interleukin (IL)-2, -4, and -7. Many reports have shown that single nucleotide polymorphisms (SNPs) of these cytokines can affect the occurrence of AR. IL-3, which is secreted by activated T cells, can mediate AR. Our study sought to investigate the association between SNPs of the IL3 gene and the occurrence of an AR episode (ARE).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
1873-2623
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
|
| pubmed:issnType |
Electronic
|
| pubmed:volume |
42
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
4501-4
|
| pubmed:meshHeading |
pubmed-meshheading:21168724-Adult,
pubmed-meshheading:21168724-Base Sequence,
pubmed-meshheading:21168724-DNA Primers,
pubmed-meshheading:21168724-Female,
pubmed-meshheading:21168724-Graft Rejection,
pubmed-meshheading:21168724-Humans,
pubmed-meshheading:21168724-Interleukin-3,
pubmed-meshheading:21168724-Kidney Transplantation,
pubmed-meshheading:21168724-Male,
pubmed-meshheading:21168724-Middle Aged,
pubmed-meshheading:21168724-Polymorphism, Single Nucleotide
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| pubmed:year |
2010
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| pubmed:articleTitle |
Association between interleukin-3 gene polymorphism and acute rejection after kidney transplantation.
|
| pubmed:affiliation |
Department of Nephrology, Kyung Hee University Medical Center, Seoul, South Korea.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|