Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-12-17
pubmed:abstractText
The mechanisms of early activation of natural killers were studied in volunteers of different athletic qualification. The initial levels of expression of KIR2DL2, PRF1, and GZMB genes regulating the functions of natural killer differ in athletes and untrained subjects. Moderate exercise stimulates transcription activities of these genes. In athletes, the expression increases more intensely than in controls. Stimulation of inhibitory (KIR2DL3) and activation (KIR2DS2) receptors was revealed. This indicated nonspecific stimulation of natural killers, probably mediated by an increase in serum concentration of heat shock protein with a molecular weight of 70 kDa.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1573-8221
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
149
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
755-8
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Expression of KIR2DL3 and KIR2DS2 natural killer receptors in exercise.
pubmed:affiliation
Institute of Physical Culture and Sports, Moscow, Russia. varja.shlepzova@gmail.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't