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pubmed-article:21165411pubmed:dateCreated2010-12-17lld:pubmed
pubmed-article:21165411pubmed:abstractTextWe studied the distribution of glial fibrillary acidic protein (GFAP) and neuron-specific nuclear histone protein NeuN in sulci of the brain cortex during the pre- and postnatal ontogeny. The expression of GFAP during morphogenetic development of the sulci and gyri is cyclic. After functional reorientation of GFAP in human fetuses at weeks 28-30 it ceases to be a marker of morphogenetically active glia and becomes a marker of glial cells exclusively. Redistribution of NeuN expression in different layers of sulci during their formation was found: enhanced expression of NeuN in the cortical layer 6 of sulci and its reduced expression in the upper layers were noted, whereas outside the cortical sulci NeuN expression was similar in all layers. At weeks 24-25 of gestation, NeuN serves as a marker of ingrowth of secondary visual fibers from the dorsal thalamus.lld:pubmed
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pubmed-article:21165411pubmed:authorpubmed-author:GodovalovaO...lld:pubmed
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pubmed-article:21165411pubmed:volume149lld:pubmed
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pubmed-article:21165411pubmed:year2010lld:pubmed
pubmed-article:21165411pubmed:articleTitleExpression of nervous tissue nuclear protein and glial fibrillary acidic protein during morphogenesis of the neocortex.lld:pubmed
pubmed-article:21165411pubmed:affiliationLaboratory of Nervous System Development, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia. godovalova@inbox.rulld:pubmed
pubmed-article:21165411pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21165411pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed