Source:http://linkedlifedata.com/resource/pubmed/id/21165411
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-12-17
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pubmed:abstractText |
We studied the distribution of glial fibrillary acidic protein (GFAP) and neuron-specific nuclear histone protein NeuN in sulci of the brain cortex during the pre- and postnatal ontogeny. The expression of GFAP during morphogenetic development of the sulci and gyri is cyclic. After functional reorientation of GFAP in human fetuses at weeks 28-30 it ceases to be a marker of morphogenetically active glia and becomes a marker of glial cells exclusively. Redistribution of NeuN expression in different layers of sulci during their formation was found: enhanced expression of NeuN in the cortical layer 6 of sulci and its reduced expression in the upper layers were noted, whereas outside the cortical sulci NeuN expression was similar in all layers. At weeks 24-25 of gestation, NeuN serves as a marker of ingrowth of secondary visual fibers from the dorsal thalamus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Glial Fibrillary Acidic Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/neuronal nuclear antigen NeuN, human
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1573-8221
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
149
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
655-8
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pubmed:meshHeading |
pubmed-meshheading:21165411-Adult,
pubmed-meshheading:21165411-Antigens, Nuclear,
pubmed-meshheading:21165411-Autopsy,
pubmed-meshheading:21165411-Female,
pubmed-meshheading:21165411-Fetus,
pubmed-meshheading:21165411-Glial Fibrillary Acidic Protein,
pubmed-meshheading:21165411-Humans,
pubmed-meshheading:21165411-Infant,
pubmed-meshheading:21165411-Middle Aged,
pubmed-meshheading:21165411-Neocortex,
pubmed-meshheading:21165411-Nerve Tissue Proteins,
pubmed-meshheading:21165411-Pregnancy,
pubmed-meshheading:21165411-Pregnancy Trimester, Second,
pubmed-meshheading:21165411-Pregnancy Trimester, Third
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pubmed:year |
2010
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pubmed:articleTitle |
Expression of nervous tissue nuclear protein and glial fibrillary acidic protein during morphogenesis of the neocortex.
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pubmed:affiliation |
Laboratory of Nervous System Development, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia. godovalova@inbox.ru
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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