21164388

Source:http://linkedlifedata.com/resource/pubmed/id/21164388

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0035647, umls-concept:C0035820, umls-concept:C0040329, umls-concept:C0205419, umls-concept:C0596263, umls-concept:C1421334, umls-concept:C1880022
pubmed:issue	2
pubmed:dateCreated	2011-1-11
pubmed:abstractText	To examine UGT2A1 expression in human tissues, determine its glucuronidation activity against tobacco carcinogens, and assess the potential functional role of UGT2A1 missense single nucleotide polymorphisms on UGT2A1 enzyme activity.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/R01 CA059917-10, http://linkedlifedata.com/resource/pubmed/grant/R01 DE013158-08, http://linkedlifedata.com/resource/pubmed/grant/R01 DE013158-09, http://linkedlifedata.com/resource/pubmed/grant/R01 DE013158-10, http://linkedlifedata.com/resource/pubmed/grant/R01 DE013158-11, http://linkedlifedata.com/resource/pubmed/grant/R01-DE13158
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101231005
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Carcinogens, http://linkedlifedata.com/resource/pubmed/chemical/Glucuronides, http://linkedlifedata.com/resource/pubmed/chemical/Glucuronosyltransferase, http://linkedlifedata.com/resource/pubmed/chemical/Polycyclic Hydrocarbons, Aromatic
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	1744-6880
pubmed:author	pubmed-author:AminShantuS, pubmed-author:Blevins-PrimeauAndrea SAS, pubmed-author:BusheyRyan TRT, pubmed-author:KrzeminskiJacekJ, pubmed-author:LazarusPhilipP, pubmed-author:RamA BAB
pubmed:issnType	Electronic
pubmed:volume	21
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	55-65
pubmed:meshHeading	pubmed-meshheading:21164388-Amino Acid Sequence, pubmed-meshheading:21164388-Blotting, Western, pubmed-meshheading:21164388-Carcinogens, pubmed-meshheading:21164388-Chromatography, Liquid, pubmed-meshheading:21164388-Conserved Sequence, pubmed-meshheading:21164388-Gene Expression Profiling, pubmed-meshheading:21164388-Gene Expression Regulation, Enzymologic, pubmed-meshheading:21164388-Glucuronides, pubmed-meshheading:21164388-Glucuronosyltransferase, pubmed-meshheading:21164388-Glycosylation, pubmed-meshheading:21164388-HEK293 Cells, pubmed-meshheading:21164388-Humans, pubmed-meshheading:21164388-Kinetics, pubmed-meshheading:21164388-Molecular Sequence Data, pubmed-meshheading:21164388-Organ Specificity, pubmed-meshheading:21164388-Polycyclic Hydrocarbons, Aromatic, pubmed-meshheading:21164388-Polymorphism, Single Nucleotide, pubmed-meshheading:21164388-Precancerous Conditions, pubmed-meshheading:21164388-Substrate Specificity, pubmed-meshheading:21164388-Tobacco
pubmed:year	2011
pubmed:articleTitle	Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.
pubmed:affiliation	Molecular Epidemiology and Cancer Control Program, Penn State Cancer Institute, Department of Pharmacology, Penn State University College of Medicine, 500 University Drive, Hershey, Pennsylvania 17033, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural