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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1978-12-2
|
| pubmed:abstractText |
Fifty eight patients with small cell carcinoma of the lung were treated with a combined-modality regimen: chemotherapy with adriamycin, cyclophosphamide, and vincristine; BCG immunotherapy; radiotherapy to the lung primary and prophylactic cranial irradiation. Ninteen patients had limited disease, and 39 had extensive disease. There were 27 (48%) partial remissions and 23 (41%) complete remissions, and median survival was 51 wk. Initial performance status and extent of disease had a definite effect on survival. Only 1 patient developed CNS metastases on prophylactic cranial irradiation. Five of 19 patients (26%) with limited disease remain alive and in complete remission at 26-45+ mo. It is becoming clear from this and other recent studies that we can significantly prolong median survival in small cell lung cancer. However, even more important is the fact that limited-extent small cell lung cancer may be a potentially curable disease.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0093-7754
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
309-13
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:211642-Adult,
pubmed-meshheading:211642-Aged,
pubmed-meshheading:211642-Anorexia,
pubmed-meshheading:211642-Antineoplastic Agents,
pubmed-meshheading:211642-BCG Vaccine,
pubmed-meshheading:211642-Bone Marrow,
pubmed-meshheading:211642-Carcinoma, Small Cell,
pubmed-meshheading:211642-Drug Therapy, Combination,
pubmed-meshheading:211642-Female,
pubmed-meshheading:211642-Humans,
pubmed-meshheading:211642-Lung Neoplasms,
pubmed-meshheading:211642-Male,
pubmed-meshheading:211642-Middle Aged,
pubmed-meshheading:211642-Radiation Injuries,
pubmed-meshheading:211642-Recurrence,
pubmed-meshheading:211642-Remission, Spontaneous,
pubmed-meshheading:211642-Sleep Stages,
pubmed-meshheading:211642-Time Factors
|
| pubmed:year |
1978
|
| pubmed:articleTitle |
Long-term results in combined-modality treatment of small cell carcinoma of the lung.
|
| pubmed:publicationType |
Journal Article
|