Optimism bias refers to unwarranted belief in the efficacy of new therapies. We assessed the impact of optimism bias on a proportion of trials that did not answer their research question successfully and explored whether poor accrual or optimism bias is responsible for inconclusive results.
Department of Medicine, Center for Evidence-based Medicine & Health Outcomes Research, University of South Florida, Tampa, FL 33612, USA. bdjulbeg@health.usf.edu
