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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0007226,
umls-concept:C0042333,
umls-concept:C0042523,
umls-concept:C0314603,
umls-concept:C0814022,
umls-concept:C1274040,
umls-concept:C1417683,
umls-concept:C1512888,
umls-concept:C1711351,
umls-concept:C2603343
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pubmed:issue |
6
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pubmed:dateCreated |
2010-12-15
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pubmed:databankReference |
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pubmed:abstractText |
Single-nucleotide polymorphisms (SNPs) within the regulatory ?2 subunit of the voltage-gated calcium channel (CACNB2) may contribute to variable treatment response to antihypertensive drugs and adverse cardiovascular outcomes.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1942-3268
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
548-55
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pubmed:dateRevised |
2011-8-4
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pubmed:meshHeading |
pubmed-meshheading:21156931-Adrenergic beta-Antagonists,
pubmed-meshheading:21156931-Aged,
pubmed-meshheading:21156931-Aged, 80 and over,
pubmed-meshheading:21156931-Antihypertensive Agents,
pubmed-meshheading:21156931-Calcium Channel Blockers,
pubmed-meshheading:21156931-Calcium Channels, L-Type,
pubmed-meshheading:21156931-Cardiovascular Diseases,
pubmed-meshheading:21156931-Ethnic Groups,
pubmed-meshheading:21156931-Female,
pubmed-meshheading:21156931-Genome-Wide Association Study,
pubmed-meshheading:21156931-Humans,
pubmed-meshheading:21156931-Hypertension,
pubmed-meshheading:21156931-Male,
pubmed-meshheading:21156931-Middle Aged,
pubmed-meshheading:21156931-Pharmacogenetics,
pubmed-meshheading:21156931-Polymorphism, Single Nucleotide,
pubmed-meshheading:21156931-Protein Subunits,
pubmed-meshheading:21156931-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Genetic variation in the beta2 subunit of the voltage-gated calcium channel and pharmacogenetic association with adverse cardiovascular outcomes in the INternational VErapamil SR-Trandolapril STudy GENEtic Substudy (INVEST-GENES).
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pubmed:affiliation |
Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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