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rdf:type |
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lifeskim:mentions |
umls-concept:C0002085,
umls-concept:C0015295,
umls-concept:C0017259,
umls-concept:C0019737,
umls-concept:C0020792,
umls-concept:C0079411,
umls-concept:C0441471,
umls-concept:C1314939,
umls-concept:C1415561,
umls-concept:C1415587,
umls-concept:C2362652
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pubmed:issue |
3
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pubmed:dateCreated |
2011-2-14
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pubmed:abstractText |
HLA-G*01:17 was discovered in a woman of Kenyan descent who was enrolled in a mother-to-child HIV-1 transmission cohort. The new allele was identical to HLA-G*01:06 at exons 2, 3, and 4 with the exception of a base pair substitution at codon 169 (CAC ? CGC) resulting in a coding change from histidine to arginine and codon 171 (TAC ? CAC), resulting in turn in a coding change from tyrosine to histidine. The World Health Organization (WHO) Nomenclature Committee has named this allele HLA-G*01:17.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1879-1166
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 American Society for Histocompatibility and Immunogenetics. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
238-40
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21156191-Alleles,
pubmed-meshheading:21156191-Amino Acid Substitution,
pubmed-meshheading:21156191-Base Sequence,
pubmed-meshheading:21156191-Chromosomes, Human, Pair 6,
pubmed-meshheading:21156191-Female,
pubmed-meshheading:21156191-Gene Conversion,
pubmed-meshheading:21156191-Genotype,
pubmed-meshheading:21156191-HLA Antigens,
pubmed-meshheading:21156191-HLA-B Antigens,
pubmed-meshheading:21156191-HLA-G Antigens,
pubmed-meshheading:21156191-Histocompatibility Antigens Class I,
pubmed-meshheading:21156191-Humans,
pubmed-meshheading:21156191-Polymerase Chain Reaction,
pubmed-meshheading:21156191-Polymorphism, Single Nucleotide,
pubmed-meshheading:21156191-Protein Conformation,
pubmed-meshheading:21156191-Sequence Alignment,
pubmed-meshheading:21156191-Sequence Analysis, DNA
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pubmed:year |
2011
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pubmed:articleTitle |
Identification of HLA-G*01:17, a new allele possibly generated by an interloci gene conversion event involving exon 3 of HLA-B.
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pubmed:affiliation |
National Microbiology Laboratory, Winnipeg, Manitoba, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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