| pubmed-article:21155826 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21155826 | lifeskim:mentions | umls-concept:C0162740 | lld:lifeskim |
| pubmed-article:21155826 | lifeskim:mentions | umls-concept:C0026046 | lld:lifeskim |
| pubmed-article:21155826 | lifeskim:mentions | umls-concept:C1705165 | lld:lifeskim |
| pubmed-article:21155826 | lifeskim:mentions | umls-concept:C1334479 | lld:lifeskim |
| pubmed-article:21155826 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:21155826 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:21155826 | lifeskim:mentions | umls-concept:C2700061 | lld:lifeskim |
| pubmed-article:21155826 | lifeskim:mentions | umls-concept:C1513354 | lld:lifeskim |
| pubmed-article:21155826 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:21155826 | pubmed:dateCreated | 2011-2-3 | lld:pubmed |
| pubmed-article:21155826 | pubmed:abstractText | • A mitogen-activated protein kinase kinase kinase (MAPKKK) double mutant, Arabidopsis homologue of nucleus and phragmoplast associated kinase (anp) anp2anp3, and the mitogen-activated protein kinase (MAPK) 4 mutant mpk4 of Arabidopsis thaliana show prominent cytokinetic defects. This prompted the analysis of mitotic and cytokinetic progression as a function of MAPK signalling. Mutants were compared with wild types untreated or treated with the specific MAPKK inhibitor PD98059. • This study included phenotype analysis, expression analysis of the MPK4 promoter, immunofluorescent localization of MPK4, tubulin and MAP65-1, and time-lapse microscopic visualization of the mitotic microtubule (MT) transitions in control, mutant and inhibitor-treated cells. • Mutant and inhibitor-treated cells showed defects in mitosis and cytokinesis, including aberrant spindle and phragmoplast formation and drastically delayed or abortive mitosis and cytokinesis. As a result, bi- and multinucleate cells were formed, ultimately disturbing the vegetative tissue patterning. MPK4 was localized to all stages of the expanding phragmoplast, in a pattern similar to that of its putative substrate MAP65-1. • In this study, MPK4 is shown to be involved in the regulation of mitosis/cytokinesis through modulation of the cell division plane and cytokinetic progression. | lld:pubmed |
| pubmed-article:21155826 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21155826 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21155826 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21155826 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21155826 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:21155826 | pubmed:issn | 1469-8137 | lld:pubmed |
| pubmed-article:21155826 | pubmed:author | pubmed-author:SamajJozefJ | lld:pubmed |
| pubmed-article:21155826 | pubmed:author | pubmed-author:BeckMartinaM | lld:pubmed |
| pubmed-article:21155826 | pubmed:author | pubmed-author:KomisGeorgeG | lld:pubmed |
| pubmed-article:21155826 | pubmed:author | pubmed-author:MenzelDiedrik... | lld:pubmed |
| pubmed-article:21155826 | pubmed:author | pubmed-author:ZiemannAnjaA | lld:pubmed |
| pubmed-article:21155826 | pubmed:copyrightInfo | © 2010 The Authors. New Phytologist © 2010 New Phytologist Trust. | lld:pubmed |
| pubmed-article:21155826 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21155826 | pubmed:volume | 189 | lld:pubmed |
| pubmed-article:21155826 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21155826 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21155826 | pubmed:pagination | 1069-83 | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:meshHeading | pubmed-meshheading:21155826... | lld:pubmed |
| pubmed-article:21155826 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21155826 | pubmed:articleTitle | Mitogen-activated protein kinase 4 is involved in the regulation of mitotic and cytokinetic microtubule transitions in Arabidopsis thaliana. | lld:pubmed |
| pubmed-article:21155826 | pubmed:affiliation | Institut für Zelluläre und Molekulare Botanik, Universität Bonn, Kirschallee 1, D53115 Bonn, Germany. | lld:pubmed |
| pubmed-article:21155826 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21155826 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:828151 | entrezgene:pubmed | pubmed-article:21155826 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21155826 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:21155826 | lld:pubmed |
