21154325

Source:http://linkedlifedata.com/resource/pubmed/id/21154325

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0004083, umls-concept:C0004936, umls-concept:C0032529, umls-concept:C1135159
pubmed:issue	6
pubmed:dateCreated	2010-12-14
pubmed:abstractText	The enzyme catechol-O-methyltransferase (COMT) transfers a methyl group from S-adenosylmethionine to the benzene ring of catecholamines including the neurotransmitters dopamine, epinephrine and norepinephrine. This methylation results in the degradation of catecholamines. The involvement of the COMT gene in the metabolic pathway of these neurotransmitters has made it an attractive candidate gene for many psychiatric disorders. This review focuses on the association between the genetic polymorphisms of COMT gene and psychiatric disorders.
pubmed:language	chi
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9425197
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Catechol O-Methyltransferase
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	1003-9406
pubmed:author	pubmed-author:JingQiangQ, pubmed-author:LeivaSS, pubmed-author:ZhongShu-rongSR
pubmed:issnType	Print
pubmed:volume	27
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	650-3
pubmed:meshHeading	pubmed-meshheading:21154325-Catechol O-Methyltransferase, pubmed-meshheading:21154325-Humans, pubmed-meshheading:21154325-Mental Disorders, pubmed-meshheading:21154325-Polymorphism, Genetic
pubmed:year	2010
pubmed:articleTitle	[Association of genetic polymorphisms of COMT gene with psychiatric disorders].
pubmed:affiliation	Department of Forensic Medicine, Kunming Medical College, Kunming, Yunnan, P.R. China.
pubmed:publicationType	Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't