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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-12-14
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pubmed:abstractText |
The polyamine system has been implicated in a number of psychiatric conditions, which display both alterations in polyamine levels and altered expression of genes related to polyamine metabolism. Studies have identified associations between genetic variants in spermidine/spermine N1-acetyltransferase (SAT1) and both anxiety and suicide, and several polymorphisms appear to play important roles in determining gene expression.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e15146
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pubmed:dateRevised |
2011-11-2
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pubmed:meshHeading |
pubmed-meshheading:21152090-Acetyltransferases,
pubmed-meshheading:21152090-Anxiety Disorders,
pubmed-meshheading:21152090-Canada,
pubmed-meshheading:21152090-France,
pubmed-meshheading:21152090-Gene Frequency,
pubmed-meshheading:21152090-Genetic Predisposition to Disease,
pubmed-meshheading:21152090-Genotype,
pubmed-meshheading:21152090-Haplotypes,
pubmed-meshheading:21152090-Humans,
pubmed-meshheading:21152090-Mood Disorders,
pubmed-meshheading:21152090-Multivariate Analysis,
pubmed-meshheading:21152090-Odds Ratio,
pubmed-meshheading:21152090-Ornithine-Oxo-Acid Transaminase,
pubmed-meshheading:21152090-Oxidoreductases Acting on CH-NH Group Donors,
pubmed-meshheading:21152090-Polyamines,
pubmed-meshheading:21152090-Polymorphism, Single Nucleotide,
pubmed-meshheading:21152090-Spermine Synthase,
pubmed-meshheading:21152090-Suicide, Attempted
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pubmed:year |
2010
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pubmed:articleTitle |
Association of polyaminergic loci with anxiety, mood disorders, and attempted suicide.
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pubmed:affiliation |
McGill Group for Suicide Studies, Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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