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rdf:type |
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lifeskim:mentions |
umls-concept:C0015111,
umls-concept:C0020459,
umls-concept:C0026809,
umls-concept:C0026882,
umls-concept:C0028756,
umls-concept:C0079866,
umls-concept:C0205082,
umls-concept:C0205314,
umls-concept:C0299583,
umls-concept:C0679622,
umls-concept:C1314792
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-14
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pubmed:abstractText |
Obesity is a multifactorial disease that arises from complex interactions between genetic predisposition and environmental factors. Leptin is central to the regulation of energy metabolism and control of body weight in mammals.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:ChenShiow-YiSY,
pubmed-author:ChengChih-YaCY,
pubmed-author:ChengIrene HIH,
pubmed-author:ChouChuan-KaiCK,
pubmed-author:ChuangYou-ChungYC,
pubmed-author:HongChen-JeeCJ,
pubmed-author:HsuChih-WeiCW,
pubmed-author:JhengHuei-FenHF,
pubmed-author:LinYa-TzuYT,
pubmed-author:LiouYing-JayYJ,
pubmed-author:TsaiPei-JanePJ,
pubmed-author:TsaiShih-JenSJ,
pubmed-author:TsaiYau-ShengYS,
pubmed-author:YangChia-NingCN
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|
pubmed:issnType |
Electronic
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pubmed:volume |
5
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
e15333
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pubmed:meshHeading |
pubmed-meshheading:21151569-Animals,
pubmed-meshheading:21151569-Body Weight,
pubmed-meshheading:21151569-Ethylnitrosourea,
pubmed-meshheading:21151569-Evolution, Molecular,
pubmed-meshheading:21151569-Exons,
pubmed-meshheading:21151569-Genetic Predisposition to Disease,
pubmed-meshheading:21151569-Homozygote,
pubmed-meshheading:21151569-Humans,
pubmed-meshheading:21151569-Hyperinsulinism,
pubmed-meshheading:21151569-Leptin,
pubmed-meshheading:21151569-Mice,
pubmed-meshheading:21151569-Mutagenesis,
pubmed-meshheading:21151569-Mutation,
pubmed-meshheading:21151569-Obesity, Morbid,
pubmed-meshheading:21151569-Receptors, Leptin
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pubmed:year |
2010
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pubmed:articleTitle |
ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin.
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pubmed:affiliation |
Institute of Brain Science, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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