Source:http://linkedlifedata.com/resource/pubmed/id/21147891
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2011-2-18
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pubmed:abstractText |
Central obesity predisposes to various cardiometabolic diseases and is a key component of the metabolic syndrome (MetS). We have previously demonstrated that three obesity-susceptible single nucleotide polymorphisms (SNPs), rs10938397 (GNPDA2), rs8050136 (FTO) and rs17782313 (MC4R), were associated with obesity and waist circumference in cross-sectional studies in the Chinese population. In this study, we investigate whether these SNPs could also predict the persistence of central obesity and MetS in subjects from the Hong Kong Cardiovascular Risk Factors Prevalence Study (CRISPS) cohort.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1479-683X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
164
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
381-8
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pubmed:meshHeading |
pubmed-meshheading:21147891-Adult,
pubmed-meshheading:21147891-Aged,
pubmed-meshheading:21147891-Female,
pubmed-meshheading:21147891-Genetic Variation,
pubmed-meshheading:21147891-Genotype,
pubmed-meshheading:21147891-Humans,
pubmed-meshheading:21147891-Longitudinal Studies,
pubmed-meshheading:21147891-Male,
pubmed-meshheading:21147891-Metabolic Syndrome X,
pubmed-meshheading:21147891-Middle Aged,
pubmed-meshheading:21147891-Obesity,
pubmed-meshheading:21147891-Polymorphism, Single Nucleotide,
pubmed-meshheading:21147891-Prospective Studies
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pubmed:year |
2011
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pubmed:articleTitle |
Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study.
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pubmed:affiliation |
Department of Medicine, LKS Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, SAR, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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