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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-5-20
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pubmed:abstractText |
Glucagon-like peptide-1 (GLP-1), a gut-derived peptide degraded by dipeptidyl peptidase-4 (DPP4), stimulates insulin secretion in response to nutrients, yet its direct effect on the liver is controversial. We investigated the effects of GLP-1 on hepatic fat and glucose metabolism and elucidated its mechanism of action.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/AMP-Activated Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Dipeptidyl Peptidase 4,
http://linkedlifedata.com/resource/pubmed/chemical/Glucagon-Like Peptide 1,
http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Prkaa2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1214-23
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pubmed:meshHeading |
pubmed-meshheading:21145820-AMP-Activated Protein Kinases,
pubmed-meshheading:21145820-Animals,
pubmed-meshheading:21145820-Base Sequence,
pubmed-meshheading:21145820-Cells, Cultured,
pubmed-meshheading:21145820-Cyclic AMP,
pubmed-meshheading:21145820-Cytokines,
pubmed-meshheading:21145820-DNA Primers,
pubmed-meshheading:21145820-Dipeptidyl Peptidase 4,
pubmed-meshheading:21145820-Enzyme Activation,
pubmed-meshheading:21145820-Fatty Liver,
pubmed-meshheading:21145820-Glucagon-Like Peptide 1,
pubmed-meshheading:21145820-Hepatocytes,
pubmed-meshheading:21145820-Inflammation Mediators,
pubmed-meshheading:21145820-Lipids,
pubmed-meshheading:21145820-Lipogenesis,
pubmed-meshheading:21145820-Liver,
pubmed-meshheading:21145820-Male,
pubmed-meshheading:21145820-Metabolic Networks and Pathways,
pubmed-meshheading:21145820-RNA, Messenger,
pubmed-meshheading:21145820-Rats,
pubmed-meshheading:21145820-Rats, Inbred F344,
pubmed-meshheading:21145820-Rats, Transgenic
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pubmed:year |
2011
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pubmed:articleTitle |
Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase.
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pubmed:affiliation |
Department of Gastroenterology and Hepatology, Tel Aviv Sourasky Medical Center, and Sackler School of Medicine, Tel Aviv, Israel.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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