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rdf:type |
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lifeskim:mentions |
umls-concept:C0032854,
umls-concept:C0042870,
umls-concept:C0086860,
umls-concept:C0087111,
umls-concept:C0332281,
umls-concept:C0524910,
umls-concept:C0871261,
umls-concept:C1527178,
umls-concept:C1561558,
umls-concept:C1704632,
umls-concept:C1705938,
umls-concept:C1706817,
umls-concept:C1882417,
umls-concept:C2911692
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pubmed:issue |
5
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pubmed:dateCreated |
2011-4-18
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pubmed:abstractText |
Vitamin D is an important immune modulator and preliminary data indicated an association between vitamin D deficiency and sustained virologic response (SVR) rates in hepatitis C virus (HCV) genotype 1 patients. We, therefore, performed a comprehensive analysis on the impact of vitamin D serum levels and of genetic polymorphisms with functional relevance within the vitamin D cascade on chronic hepatitis C and its treatment.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
887-93
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pubmed:dateRevised |
2011-10-24
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pubmed:meshHeading |
pubmed-meshheading:21145801-25-Hydroxyvitamin D3 1-alpha-Hydroxylase,
pubmed-meshheading:21145801-Adult,
pubmed-meshheading:21145801-Aged,
pubmed-meshheading:21145801-Antiviral Agents,
pubmed-meshheading:21145801-Calcifediol,
pubmed-meshheading:21145801-Drug Resistance, Viral,
pubmed-meshheading:21145801-Female,
pubmed-meshheading:21145801-Genotype,
pubmed-meshheading:21145801-Hepacivirus,
pubmed-meshheading:21145801-Hepatitis C, Chronic,
pubmed-meshheading:21145801-Humans,
pubmed-meshheading:21145801-Interferon-alpha,
pubmed-meshheading:21145801-Male,
pubmed-meshheading:21145801-Middle Aged,
pubmed-meshheading:21145801-Polymorphism, Genetic,
pubmed-meshheading:21145801-Promoter Regions, Genetic,
pubmed-meshheading:21145801-Receptors, Calcitriol,
pubmed-meshheading:21145801-Retrospective Studies,
pubmed-meshheading:21145801-Vitamin D Deficiency,
pubmed-meshheading:21145801-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy.
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pubmed:affiliation |
Klinikum der J.W. Goethe-Universität Frankfurt am Main, Medizinische Klinik 1, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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