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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
25
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pubmed:dateCreated |
2010-12-14
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pubmed:abstractText |
In this study, we have investigated the effects of cannabidiol (CBD) on myocardial dysfunction, inflammation, oxidative/nitrative stress, cell death, and interrelated signaling pathways, using a mouse model of type I diabetic cardiomyopathy and primary human cardiomyocytes exposed to high glucose.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1558-3597
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pubmed:author |
pubmed-author:BátkaiSándorS,
pubmed-author:BeckerLaurenL,
pubmed-author:HaskóGyörgyG,
pubmed-author:HorváthBélaB,
pubmed-author:KashiwayaYoshihiroY,
pubmed-author:LiaudetLucasL,
pubmed-author:MatsumotoShingoS,
pubmed-author:MechoulamRaphaelR,
pubmed-author:MukhopadhyayBaniB,
pubmed-author:MukhopadhyayParthaP,
pubmed-author:PacherPálP,
pubmed-author:PatelVivekV,
pubmed-author:RajeshMohanrajM,
pubmed-author:SaitoKeitaK,
pubmed-author:VevesAristidisA,
pubmed-author:WinkDavid ADA
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pubmed:copyrightInfo |
Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2115-25
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21144973-Animals,
pubmed-meshheading:21144973-Apoptosis,
pubmed-meshheading:21144973-Blood Glucose,
pubmed-meshheading:21144973-Body Weight,
pubmed-meshheading:21144973-Cannabidiol,
pubmed-meshheading:21144973-Cells, Cultured,
pubmed-meshheading:21144973-Diabetic Cardiomyopathies,
pubmed-meshheading:21144973-Disease Models, Animal,
pubmed-meshheading:21144973-Drug Evaluation, Preclinical,
pubmed-meshheading:21144973-Fibrosis,
pubmed-meshheading:21144973-Glucose,
pubmed-meshheading:21144973-Hemodynamics,
pubmed-meshheading:21144973-Humans,
pubmed-meshheading:21144973-Insulin,
pubmed-meshheading:21144973-MAP Kinase Signaling System,
pubmed-meshheading:21144973-Male,
pubmed-meshheading:21144973-Mice,
pubmed-meshheading:21144973-Mice, Inbred C57BL,
pubmed-meshheading:21144973-Myocardium,
pubmed-meshheading:21144973-Myocytes, Cardiac,
pubmed-meshheading:21144973-NF-kappa B,
pubmed-meshheading:21144973-Oxidative Stress,
pubmed-meshheading:21144973-Pancreas,
pubmed-meshheading:21144973-Reactive Oxygen Species
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pubmed:year |
2010
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pubmed:articleTitle |
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.
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pubmed:affiliation |
Laboratory of Physiological Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892-9413, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
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