|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5653
|
|
pubmed:dateCreated |
1978-11-18
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|
pubmed:abstractText |
Rat ovarian granulosa cells and mouse myocardial cells respond to cell-specific hormones by cyclic AMP-dependent mechanisms. In coculture, these heterologous cells communicate by means of gap junctions. Exposure of the cocultures to a hormone specific for one cell type causes the heterologous cells to respond through a cell contact-dependent mechanism. These studies suggest that this cross-stimulation results from the intercellular communication of a mediator that is common to both cell types. The communicated mediator may be cyclic AMP.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0028-0836
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
6
|
|
pubmed:volume |
272
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
501-6
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:211417-Cell Communication,
pubmed-meshheading:211417-Cells, Cultured,
pubmed-meshheading:211417-Cyclic AMP,
pubmed-meshheading:211417-Dose-Response Relationship, Drug,
pubmed-meshheading:211417-Female,
pubmed-meshheading:211417-Follicle Stimulating Hormone,
pubmed-meshheading:211417-Granulosa Cells,
pubmed-meshheading:211417-Intercellular Junctions,
pubmed-meshheading:211417-Membrane Potentials,
pubmed-meshheading:211417-Myocardial Contraction,
pubmed-meshheading:211417-Myocardium,
pubmed-meshheading:211417-Norepinephrine,
pubmed-meshheading:211417-Plasminogen Activators
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pubmed:year |
1978
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pubmed:articleTitle |
Transmission of hormonal stimulation by cell-to-cell communication.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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