| pubmed-article:21141674 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21141674 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:21141674 | lifeskim:mentions | umls-concept:C0679083 | lld:lifeskim |
| pubmed-article:21141674 | lifeskim:mentions | umls-concept:C0870071 | lld:lifeskim |
| pubmed-article:21141674 | lifeskim:mentions | umls-concept:C1705938 | lld:lifeskim |
| pubmed-article:21141674 | lifeskim:mentions | umls-concept:C1527178 | lld:lifeskim |
| pubmed-article:21141674 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:21141674 | pubmed:dateCreated | 2010-12-14 | lld:pubmed |
| pubmed-article:21141674 | pubmed:abstractText | This work presents an overview of the use of liposomes for targeted delivery of photosensitizers to tumors for Photodynamic Therapy (PDT). It assesses the results of a quantitative model to explain the interaction of short-pulsed lasers (in the nanosecond and picosecond domains) with a liposome-dye complex in terms of a localized photo-induced thermal mechanism. Incorporation of an organic dye (sulforhodamine) within lipid vesicles has been investigated in conjunction with the effect of laser irradiation on the integrity of the liposome-dye complex. The variation of the absorption coefficient as a function of wavelength for dye-encapsulated liposomes before and after laser-induced release of dye was studied and modeled. The commercial software Mathematica was used to develop a Gaussian model for the energy absorption by the liposome-dye complex. Dye release from 3 microm - liposome encapsulating 25 mM aqueous solution of sulforhodamine dye was studied using 8 ns laser pulses at the second harmonic of the Nd:YAG laser (at 532 nm) and compared with dye release employing 25 ps - laser pulses. In addition, the temperature-dependence of the dye release has been included in the photo-thermal model. | lld:pubmed |
| pubmed-article:21141674 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21141674 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21141674 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21141674 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21141674 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21141674 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21141674 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:21141674 | pubmed:issn | 1556-5297 | lld:pubmed |
| pubmed-article:21141674 | pubmed:author | pubmed-author:SridharRR | lld:pubmed |
| pubmed-article:21141674 | pubmed:author | pubmed-author:MisraPP | lld:pubmed |
| pubmed-article:21141674 | pubmed:author | pubmed-author:MensahF EFE | lld:pubmed |
| pubmed-article:21141674 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:21141674 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:21141674 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21141674 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21141674 | pubmed:pagination | 203-12 | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:meshHeading | pubmed-meshheading:21141674... | lld:pubmed |
| pubmed-article:21141674 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:21141674 | pubmed:articleTitle | Simulation and modeling of laser-tissue interactions based on a liposome-dye system. | lld:pubmed |
| pubmed-article:21141674 | pubmed:affiliation | University of the District of Columbia, Washington, DC, USA. | lld:pubmed |
| pubmed-article:21141674 | pubmed:publicationType | Journal Article | lld:pubmed |
