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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-12-8
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pubmed:abstractText |
The cytochrome p450 family 1 subfamily B (CYP1B1) gene is a well known cause of autosomal recessive primary congenital glaucoma. It has also been postulated as a modifier of disease severity in primary open angle glaucoma (POAG), particularly in juvenile onset families. However, the role of common variation in the gene in relation to POAG has not been thoroughly explored.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2286-93
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21139974-Aged,
pubmed-meshheading:21139974-Aged, 80 and over,
pubmed-meshheading:21139974-Alleles,
pubmed-meshheading:21139974-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:21139974-Case-Control Studies,
pubmed-meshheading:21139974-Cytochrome P-450 Enzyme System,
pubmed-meshheading:21139974-Demography,
pubmed-meshheading:21139974-Female,
pubmed-meshheading:21139974-Gene Frequency,
pubmed-meshheading:21139974-Genetic Association Studies,
pubmed-meshheading:21139974-Genetic Predisposition to Disease,
pubmed-meshheading:21139974-Glaucoma, Open-Angle,
pubmed-meshheading:21139974-Haplotypes,
pubmed-meshheading:21139974-Humans,
pubmed-meshheading:21139974-Linkage Disequilibrium,
pubmed-meshheading:21139974-Male,
pubmed-meshheading:21139974-Polymorphism, Single Nucleotide
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pubmed:year |
2010
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pubmed:articleTitle |
Tag SNPs detect association of the CYP1B1 gene with primary open angle glaucoma.
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pubmed:affiliation |
Department of Ophthalmology, Flinders University, Adelaide, Australia. kathryn.burdon@flinders.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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