21139584

Source:http://linkedlifedata.com/resource/pubmed/id/21139584

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0021467, umls-concept:C0021469, umls-concept:C0127400, umls-concept:C0243044, umls-concept:C0334634, umls-concept:C0441655, umls-concept:C1529590, umls-concept:C1825534
pubmed:issue	1
pubmed:dateCreated	2011-1-5
pubmed:abstractText	Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma with poor prognosis, requiring novel anticancer strategies.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370635
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Boronic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Coumarins, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin D1, http://linkedlifedata.com/resource/pubmed/chemical/GUT-70, http://linkedlifedata.com/resource/pubmed/chemical/HSP90 Heat-Shock Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Oncogene Protein v-akt, http://linkedlifedata.com/resource/pubmed/chemical/PMAIP1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-bcl-2, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-raf, http://linkedlifedata.com/resource/pubmed/chemical/Pyrazines, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53, http://linkedlifedata.com/resource/pubmed/chemical/bcl-2 Homologous Antagonist-Killer..., http://linkedlifedata.com/resource/pubmed/chemical/bortezomib
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1532-1827
pubmed:author	pubmed-author:AndreeffMM, pubmed-author:AsouHH, pubmed-author:InabaTT, pubmed-author:JinLL, pubmed-author:KimuraSS, pubmed-author:KonoplevaMM, pubmed-author:KurodaJJ, pubmed-author:MiidaTT, pubmed-author:TabeYY, pubmed-author:ZhouYY
pubmed:issnType	Electronic
pubmed:day	4
pubmed:volume	104
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	91-100
pubmed:dateRevised	2011-2-18
pubmed:meshHeading	pubmed-meshheading:21139584-Antineoplastic Agents, pubmed-meshheading:21139584-Apoptosis, pubmed-meshheading:21139584-Blotting, Western, pubmed-meshheading:21139584-Boronic Acids, pubmed-meshheading:21139584-Cell Cycle, pubmed-meshheading:21139584-Cell Proliferation, pubmed-meshheading:21139584-Coumarins, pubmed-meshheading:21139584-Cyclin D1, pubmed-meshheading:21139584-Drug Synergism, pubmed-meshheading:21139584-Drug Therapy, Combination, pubmed-meshheading:21139584-Flow Cytometry, pubmed-meshheading:21139584-HSP90 Heat-Shock Proteins, pubmed-meshheading:21139584-Humans, pubmed-meshheading:21139584-Immunoenzyme Techniques, pubmed-meshheading:21139584-Immunoprecipitation, pubmed-meshheading:21139584-Lymphoma, Mantle-Cell, pubmed-meshheading:21139584-Mutation, pubmed-meshheading:21139584-Oncogene Protein v-akt, pubmed-meshheading:21139584-Proto-Oncogene Proteins c-bcl-2, pubmed-meshheading:21139584-Proto-Oncogene Proteins c-raf, pubmed-meshheading:21139584-Pyrazines, pubmed-meshheading:21139584-RNA, Messenger, pubmed-meshheading:21139584-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:21139584-Tumor Cells, Cultured, pubmed-meshheading:21139584-Tumor Suppressor Protein p53, pubmed-meshheading:21139584-bcl-2 Homologous Antagonist-Killer Protein
pubmed:year	2011
pubmed:articleTitle	Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma.
pubmed:affiliation	Department of Clinical Laboratory Medicine, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't