Source:http://linkedlifedata.com/resource/pubmed/id/21135065
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2011-2-18
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pubmed:abstractText |
The calcium-sensing receptor (CASR) is a key controller of calcium homeostasis by regulating parathyroid hormone (PTH) secretion and renal calcium reabsorption. CASR(T888) is a protein kinase C (PKC) phosphorylation site in the receptor's intracellular domain that has previously been identified as a critical negative regulator of CASR downstream signaling in vitro, but whose importance in vivo is unknown.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1479-683X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
164
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
429-35
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pubmed:meshHeading |
pubmed-meshheading:21135065-Adult,
pubmed-meshheading:21135065-Humans,
pubmed-meshheading:21135065-Hypocalcemia,
pubmed-meshheading:21135065-Male,
pubmed-meshheading:21135065-Mutation,
pubmed-meshheading:21135065-Phosphorylation,
pubmed-meshheading:21135065-Protein Kinase C,
pubmed-meshheading:21135065-Receptors, Calcium-Sensing,
pubmed-meshheading:21135065-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
A novel mutation of the primary protein kinase C phosphorylation site in the calcium-sensing receptor causes autosomal dominant hypocalcemia.
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pubmed:affiliation |
Department of Endocrinology, Royal Brisbane and Women's Hospital, Herston, Queensland 4029, Australia.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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