Source:http://linkedlifedata.com/resource/pubmed/id/21134470
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| Predicate | Object |
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| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2011-1-31
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| pubmed:abstractText |
Recently proposed dynamic magnetic resonance (MR) inverse imaging (InI) is a novel parallel imaging reconstruction technique capable of improving the temporal resolution of blood-oxygen level-dependent (BOLD) contrast functional MRI (fMRI) to the order of milliseconds at the cost of moderate spatial resolution. Volumetric InI reconstructs spatial information from projection data by solving ill-posed inverse problems using simultaneous acquisitions from a RF coil array. Previously a spatial filtering technique based on linearly constrained minimum variance (LCMV) beamformer was suggested to localize the hemodynamic changes of dynamic InI data with improved spatial resolution and sensitivity. Here we report an advancement of the spatial filtering method, which combines the eigenspace projection of the measured data and the L1-norm minimization of the spatial filters' output noise amplitude, to further improve the detection power of BOLD contrast fMRI data. Using numerical simulation and in vivo data, we demonstrate that this eigenspace linearly constrained minimum amplitude (eLCMA) beamformer can reconstruct spatiotemporal hemodynamic signals with high statistical significance values and high spatial resolution in event-related two-choice reaction time visuomotor experiments.
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| pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/P41RR14075,
http://linkedlifedata.com/resource/pubmed/grant/R01 HD040712-08,
http://linkedlifedata.com/resource/pubmed/grant/R01 NS037462-04,
http://linkedlifedata.com/resource/pubmed/grant/R01 NS037462-11,
http://linkedlifedata.com/resource/pubmed/grant/R01 NS048279-04,
http://linkedlifedata.com/resource/pubmed/grant/R01DA14178,
http://linkedlifedata.com/resource/pubmed/grant/R01EB000790,
http://linkedlifedata.com/resource/pubmed/grant/R01EB006847,
http://linkedlifedata.com/resource/pubmed/grant/R01HD040712,
http://linkedlifedata.com/resource/pubmed/grant/R01MH083744,
http://linkedlifedata.com/resource/pubmed/grant/R01NS037462,
http://linkedlifedata.com/resource/pubmed/grant/R21 EB007298-01A1,
http://linkedlifedata.com/resource/pubmed/grant/R21EB007298
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Mar
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| pubmed:issn |
1095-9572
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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| pubmed:issnType |
Electronic
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| pubmed:day |
1
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| pubmed:volume |
55
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
87-100
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| pubmed:dateRevised |
2011-9-26
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| pubmed:meshHeading |
pubmed-meshheading:21134470-Adult,
pubmed-meshheading:21134470-Algorithms,
pubmed-meshheading:21134470-Brain Mapping,
pubmed-meshheading:21134470-Computer Simulation,
pubmed-meshheading:21134470-Evoked Potentials, Motor,
pubmed-meshheading:21134470-Evoked Potentials, Visual,
pubmed-meshheading:21134470-Female,
pubmed-meshheading:21134470-Humans,
pubmed-meshheading:21134470-Magnetic Resonance Imaging,
pubmed-meshheading:21134470-Male,
pubmed-meshheading:21134470-Models, Neurological,
pubmed-meshheading:21134470-Motor Cortex,
pubmed-meshheading:21134470-Movement,
pubmed-meshheading:21134470-Visual Cortex,
pubmed-meshheading:21134470-Visual Perception
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| pubmed:year |
2011
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| pubmed:articleTitle |
Functional magnetic resonance inverse imaging of human visuomotor systems using eigenspace linearly constrained minimum amplitude (eLCMA) beamformer.
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| pubmed:affiliation |
Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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