Source:http://linkedlifedata.com/resource/pubmed/id/21133843
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2010-12-7
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pubmed:abstractText |
Processing of the pre-microRNA (pre-miRNA) through Dicer1 generates a miRNA duplex, consisting of a miRNA and miRNA* strand (also termed guide strand and passenger strand, respectively). Despite the general consensus that miRNA*s have no regulatory activity, recent publications have provided evidence that the abundance, possible function, and physiological relevance of miRNA*s have been underestimated. This review provides an account of our current understanding of miRNA* origination and activity, mounting evidence for their unique functions and regulatory mechanisms, and examples of specific miRNA*s from the literature.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1045-4403
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-8
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
miRNA*: a passenger stranded in RNA-induced silencing complex?
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pubmed:affiliation |
Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada, V5Z 1L3.
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pubmed:publicationType |
Journal Article,
Review
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