Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-12-7
pubmed:abstractText
A quantitative investigation on the inhibitory activity of thymol against some microorganisms that could represent a potential spoilage risk both in acid and mild thermally treated foods is presented in this work. In order to assess potential biostatic or biocidal activity of thymol, both the growth kinetics and dose-response profiles were obtained and analyzed. A suitable macrodilution methodology based on a turbidimetric technique was adopted to produce inhibitory data used for characterizing microbial susceptibility against thymol at sub-MIC levels. Microbial growth was monitored through absorbance measurements at 420 nm as a function of contact time with the active compound. Moreover, for each tested microorganism, the noninhibitory concentration (NIC) and the MIC were quantified. Results prove that thymol can exert a significant antimicrobial effect on each phase of the growth cycle. The microbial susceptibility and resistance were found to be nonlinearly dose related. It is worth noting that significant biostatic effects were observed at sub-MIC levels.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0362-028X
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1664-70
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
A study on the antimicrobial activity of thymol intended as a natural preservative.
pubmed:affiliation
Department of Food Science and Istituto per la Ricerca e le Applicazioni Biotecnologiche per la Sicurezza e la Valorizzazione dei Prodotti Tipici e di Qualità, University of Foggia, Via Napoli, 25-71100 Foggia, Italy.
pubmed:publicationType
Journal Article