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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2011-1-17
pubmed:abstractText
We describe two pediatric patients with an uncommon electrophysiological seizure propagation pattern. Both had dialeptic seizures as the main or only symptom. Case 1 had a small mass in the left medial temporal structures; case 2 had no lesion on magnetic resonance imaging. In both, the electroencephalogram showed not only left temporal spikes, but also bilaterally synchronous 3-Hz spike-and-wave complexes (SWCs) from onset and unusual secondarily generalized 3-Hz SWC patterns arising from the left temporal region. Case 1 was seizure free following resection of the mass; focal or generalized epileptiform electroencephalographic abnormalities were no longer present. In case 2, magnetoencephalography localized the spikes to the left superior and midtemporal gyrus, which ictal single-photon-emission computed tomography suggested was the origin of onset. These cases illustrate the close relationship between the focal epileptic area and 3-Hz SWCs and suggest that the focal area can trigger 3-Hz SWCs. The therapeutic strategy may need to be altered in such patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1525-5069
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
103-6
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Generalized 3-Hz spike-and-wave complexes emanating from focal epileptic activity in pediatric patients.
pubmed:affiliation
Epilepsy Center, Department of Neurology, The Cleveland Clinic, Cleveland, OH 44195, USA.
pubmed:publicationType
Journal Article