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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-6
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pubmed:abstractText |
The hedgehog (Hh) signaling pathway is activated in some adult cancers. On the other hand, the Hh signaling pathway plays an important role in the development of the neural crest in embryos. The aim of this study is to show the activation of Hh signaling pathway in neuroblastoma (NB), a pediatric malignancy arising from neural crest cells, and to reveal the meaning of the Hh signaling pathway in NB development.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1531-5037
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2299-304
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pubmed:meshHeading |
pubmed-meshheading:21129534-Cell Differentiation,
pubmed-meshheading:21129534-Cell Transformation, Neoplastic,
pubmed-meshheading:21129534-Child, Preschool,
pubmed-meshheading:21129534-Female,
pubmed-meshheading:21129534-Ganglioneuroblastoma,
pubmed-meshheading:21129534-Gene Amplification,
pubmed-meshheading:21129534-Genes, myc,
pubmed-meshheading:21129534-Hedgehog Proteins,
pubmed-meshheading:21129534-Humans,
pubmed-meshheading:21129534-Infant,
pubmed-meshheading:21129534-Japan,
pubmed-meshheading:21129534-Male,
pubmed-meshheading:21129534-Neoplasm Proteins,
pubmed-meshheading:21129534-Neoplasm Staging,
pubmed-meshheading:21129534-Neuroblastoma,
pubmed-meshheading:21129534-Prognosis,
pubmed-meshheading:21129534-Receptors, Cell Surface,
pubmed-meshheading:21129534-Signal Transduction,
pubmed-meshheading:21129534-Survival Analysis,
pubmed-meshheading:21129534-Transcription Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Hedgehog signaling pathway in neuroblastoma differentiation.
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pubmed:affiliation |
Department of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan. ryotas@pedsurg.med.kyushu-u.ac.jp
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pubmed:publicationType |
Journal Article
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