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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-9-15
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pubmed:abstractText |
There is a high demand for tumor specific PET tracers in oncology imaging. Besides glucose, certain amino acids also serve as energy sources and anabolic precursors for tumors. Therefore, (18)F-labeled amino acids are interesting probes for tumor specific PET imaging. As glutamine and glutamate play a key role in the adapted intermediary metabolism of tumors, the radiosynthesis of 4-[(18)F]fluoro l-glutamic acid (BAY 85-8050) as a new specific PET tracer was established. Cell-uptake studies revealed specific tumor cell accumulation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1520-4804
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pubmed:author |
pubmed-author:AmetameySimonS,
pubmed-author:BelokonYuri NYN,
pubmed-author:BerndtMathiasM,
pubmed-author:DinkelborgLudger MLM,
pubmed-author:FedorovaOlga SOS,
pubmed-author:FriebeMatthiasM,
pubmed-author:GrahamKeithK,
pubmed-author:KoglinNormanN,
pubmed-author:KrasikovaRaisa NRN,
pubmed-author:KuznetsovaOlga FOF,
pubmed-author:LehmannLutzL,
pubmed-author:MaleevViktor IVI,
pubmed-author:MuLinjingL,
pubmed-author:MuellerAndreA,
pubmed-author:SchubigerP AugustPA
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pubmed:issnType |
Electronic
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pubmed:day |
13
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
406-10
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pubmed:meshHeading |
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pubmed:year |
2011
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pubmed:articleTitle |
4-[18F]fluoroglutamic acid (BAY 85-8050), a new amino acid radiotracer for PET imaging of tumors: synthesis and in vitro characterization.
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pubmed:affiliation |
Institute of Human Brain of the Russian Academy of Science, St. Petersburg, Russia.
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pubmed:publicationType |
Journal Article
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