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pubmed:abstractText |
The traditional view of bone metabolism as a primarily endocrine activity has been expanded in recent years following the identification of nervous system controlling bone metabolism by leptin studies. Especially, hypothalamic appetite regulating-peptides, such as NPY, CART and NMU have been demonstrated to be bone-regulating neuropeptides. Recently, other neuropeptides, such as serotonin and oxytocin, are reported to be associated with bone metabolism.
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pubmed:affiliation |
Section of Nephrology, Endocrinology and Metabolism, Department of Internal Medicine, School of Medicine, Keio Univeristy, Japan.
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