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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-12-24
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pubmed:abstractText |
Three perglycosylated nordihydroguaiaretic acids (NDGA) were synthesized through the Huiseng 1,3-dipolar cycloaddition reaction. These sugar-NDGA conjugates containing triazole-linkages possessed good solubility in water. NDGA-(triazol-galactose)(4) (12b) and NDGA-(triazol-glucose)(4) (12c) were found to act as inhibitors against human hepatocellular carcinoma Hep3B cells in culture.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1464-3405
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010. Published by Elsevier Ltd.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
380-2
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pubmed:meshHeading |
pubmed-meshheading:21123067-Antineoplastic Agents,
pubmed-meshheading:21123067-Carcinoma, Hepatocellular,
pubmed-meshheading:21123067-Cell Line, Tumor,
pubmed-meshheading:21123067-Galactosides,
pubmed-meshheading:21123067-Glucosides,
pubmed-meshheading:21123067-Glycosylation,
pubmed-meshheading:21123067-Humans,
pubmed-meshheading:21123067-Liver Neoplasms,
pubmed-meshheading:21123067-Nordihydroguaiaretic Acid,
pubmed-meshheading:21123067-Triazoles
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pubmed:year |
2011
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pubmed:articleTitle |
Glycosylated nordihydroguaiaretic acids as anti-cancer agents.
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pubmed:affiliation |
Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan, ROC. jrhwu@mx.nthu.edu.tw
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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