21119661

Source:http://linkedlifedata.com/resource/pubmed/id/21119661

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007138, umls-concept:C0018270, umls-concept:C0028778, umls-concept:C0060369, umls-concept:C0243077, umls-concept:C1328819, umls-concept:C1515655, umls-concept:C1533691
pubmed:issue	1
pubmed:dateCreated	2011-1-5
pubmed:abstractText	Activating mutations of FGFR3 are frequently identified in superficial urothelial carcinoma (UC) and increased expression of FGFR1 and FGFR3 are common in both superficial and invasive UC.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/C6228/A5437, http://linkedlifedata.com/resource/pubmed/grant/C6228/A5569
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370635
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/4-amino-5-fluoro-3-(5-(4-methylpiper..., http://linkedlifedata.com/resource/pubmed/chemical/Benzimidazoles, http://linkedlifedata.com/resource/pubmed/chemical/PD 173074, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines, http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles, http://linkedlifedata.com/resource/pubmed/chemical/Quinolones, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Fibroblast Growth..., http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Fibroblast Growth..., http://linkedlifedata.com/resource/pubmed/chemical/SU 5402
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1532-1827
pubmed:author	pubmed-author:ChesterJ DJD, pubmed-author:CooperP APA, pubmed-author:KnowlesM AMA, pubmed-author:LamontF RFR, pubmed-author:ShnyderS DSD, pubmed-author:TomlinsonD CDC
pubmed:issnType	Electronic
pubmed:day	4
pubmed:volume	104
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	75-82
pubmed:dateRevised	2011-2-18
pubmed:meshHeading	pubmed-meshheading:21119661-Animals, pubmed-meshheading:21119661-Apoptosis, pubmed-meshheading:21119661-Benzimidazoles, pubmed-meshheading:21119661-Blotting, Western, pubmed-meshheading:21119661-Carcinoma, Transitional Cell, pubmed-meshheading:21119661-Cell Cycle, pubmed-meshheading:21119661-Cell Proliferation, pubmed-meshheading:21119661-Cells, Cultured, pubmed-meshheading:21119661-Humans, pubmed-meshheading:21119661-Immunoenzyme Techniques, pubmed-meshheading:21119661-Male, pubmed-meshheading:21119661-Mice, pubmed-meshheading:21119661-Mice, Inbred BALB C, pubmed-meshheading:21119661-Mutation, pubmed-meshheading:21119661-Phosphorylation, pubmed-meshheading:21119661-Protein-Tyrosine Kinases, pubmed-meshheading:21119661-Pyrimidines, pubmed-meshheading:21119661-Pyrroles, pubmed-meshheading:21119661-Quinolones, pubmed-meshheading:21119661-Receptor, Fibroblast Growth Factor, Type 1, pubmed-meshheading:21119661-Receptor, Fibroblast Growth Factor, Type 3, pubmed-meshheading:21119661-Urinary Bladder Neoplasms, pubmed-meshheading:21119661-Urothelium, pubmed-meshheading:21119661-Xenograft Model Antitumor Assays
pubmed:year	2011
pubmed:articleTitle	Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.
pubmed:affiliation	Cancer Research UK Clinical Centre, Leeds Institute of Molecular Medicine, St James's University Hospital, Beckett Street, Leeds LS9 7TF, UK.
pubmed:publicationType	Journal Article, Comparative Study, In Vitro, Research Support, Non-U.S. Gov't