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pubmed-article:2111867pubmed:abstractTextThe permanent survival rate of endotoxemic rats was studied. In 40 untreated control rats the survival rate 7 days after the endotoxin administration was 33%. The survival rate was increased to 40% with recombinant human superoxide dismutase (r-HSOD), to 55% (p less than 0.05) with the prostacyclin analogue Taprostene and to 70% (p less than 0.01) with the combination of r-HSOD and Taprostene (20 rats for each treatment group). r-HSOD and Taprostene provide significant and permanent protection in rat endotoxic shock.lld:pubmed
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pubmed-article:2111867pubmed:articleTitleThe prostacyclin analogue taprostene and recombinant human superoxide dismutase increase the permanent survival rate of endotoxemic rats.lld:pubmed
pubmed-article:2111867pubmed:affiliationCenter of Research, Grünenthal GmbH, Aachen, FRG.lld:pubmed
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