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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
20
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pubmed:dateCreated |
1990-7-3
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pubmed:abstractText |
The permanent survival rate of endotoxemic rats was studied. In 40 untreated control rats the survival rate 7 days after the endotoxin administration was 33%. The survival rate was increased to 40% with recombinant human superoxide dismutase (r-HSOD), to 55% (p less than 0.05) with the prostacyclin analogue Taprostene and to 70% (p less than 0.01) with the combination of r-HSOD and Taprostene (20 rats for each treatment group). r-HSOD and Taprostene provide significant and permanent protection in rat endotoxic shock.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0024-3205
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1421-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2111867-Animals,
pubmed-meshheading:2111867-Chi-Square Distribution,
pubmed-meshheading:2111867-Drug Synergism,
pubmed-meshheading:2111867-Endotoxins,
pubmed-meshheading:2111867-Epoprostenol,
pubmed-meshheading:2111867-Lung,
pubmed-meshheading:2111867-Male,
pubmed-meshheading:2111867-Rats,
pubmed-meshheading:2111867-Rats, Inbred Strains,
pubmed-meshheading:2111867-Recombinant Proteins,
pubmed-meshheading:2111867-Shock, Septic,
pubmed-meshheading:2111867-Superoxide Dismutase,
pubmed-meshheading:2111867-Survival Rate
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pubmed:year |
1990
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pubmed:articleTitle |
The prostacyclin analogue taprostene and recombinant human superoxide dismutase increase the permanent survival rate of endotoxemic rats.
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pubmed:affiliation |
Center of Research, Grünenthal GmbH, Aachen, FRG.
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pubmed:publicationType |
Journal Article
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