Linked Life Data

21118416

Source:http://linkedlifedata.com/resource/pubmed/id/21118416

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-2-25
pubmed:abstractText
Periodontitis is a multifactorial disease influenced partly by genetics. Activation of pattern recognition receptors (PRRs) can lead to the up-regulation of inflammatory pathways, resulting in periodontal tissue destruction. Hence, functional polymorphisms located in PRRs can explain differences in host susceptibility to periodontitis. This study investigated single nucleotide polymorphisms of PRRs including toll-like receptor (TLR)2 (G2408A), TLR4 (A896G), TLR9 (T1486C), TLR9 (T1237C) and CD14 (C260T) in patients with chronic periodontitis and in periodontally healthy subjects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Adenine, http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD14, http://linkedlifedata.com/resource/pubmed/chemical/Cytosine, http://linkedlifedata.com/resource/pubmed/chemical/Guanine, http://linkedlifedata.com/resource/pubmed/chemical/TLR2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/TLR4 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/TLR9 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Thymine, http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 2, http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4, http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 9, http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptors
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1600-0765
pubmed:author
pubmed:copyrightInfo
© 2010 John Wiley & Sons A/S.
pubmed:issnType
Electronic
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
184-92
pubmed:meshHeading
pubmed-meshheading:21118416-Adenine, pubmed-meshheading:21118416-Antigens, CD14, pubmed-meshheading:21118416-Chronic Periodontitis, pubmed-meshheading:21118416-Cytosine, pubmed-meshheading:21118416-Dental Plaque Index, pubmed-meshheading:21118416-Female, pubmed-meshheading:21118416-Gene Frequency, pubmed-meshheading:21118416-Genetic Predisposition to Disease, pubmed-meshheading:21118416-Genotype, pubmed-meshheading:21118416-Guanine, pubmed-meshheading:21118416-Homozygote, pubmed-meshheading:21118416-Humans, pubmed-meshheading:21118416-Male, pubmed-meshheading:21118416-Middle Aged, pubmed-meshheading:21118416-Periodontal Attachment Loss, pubmed-meshheading:21118416-Periodontal Index, pubmed-meshheading:21118416-Periodontal Pocket, pubmed-meshheading:21118416-Polymorphism, Single Nucleotide, pubmed-meshheading:21118416-Smoking, pubmed-meshheading:21118416-Thymine, pubmed-meshheading:21118416-Toll-Like Receptor 2, pubmed-meshheading:21118416-Toll-Like Receptor 4, pubmed-meshheading:21118416-Toll-Like Receptor 9, pubmed-meshheading:21118416-Toll-Like Receptors
pubmed:year
2011
pubmed:articleTitle
Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis.
pubmed:affiliation
Virginia Commonwealth University, School of Dentistry, Department of Periodontics, Richmond, VA 23298-0566, USA. ssahingur@vcu.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't