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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-12-1
pubmed:abstractText
Hemodialysis techniques have improved remarkably in recent decades and the number of long-term survivors among patients with end-stage renal disease has increased. The mortality rate of hemodialysis patients has been reported to be low in Japan. However, the long-term survival rate of dialysis patients is still low: 23.6% for 15 years and 17.4% for 20 years, even in Japan, and background information on patients undergoing hemodialysis therapy for more than 20 years is scarce in this country. In the present study, we investigated the characteristics of 20-year survivors undergoing maintenance hemodialysis at our medical center. We compared the characteristics of hemodialysis patients who had survived for more than 20 years after the initiation of hemodialysis with those of patients who started hemodialysis at the same time and had already died. No patient among those who were still alive had diabetes mellitus while 15% of patients who had died had diabetes mellitus at the time of initiation of hemodialysis. Age, cardiothoracic ratio, and serum levels of total cholesterol and triglyceride 6 months after the initiation of hemodialysis, as well as decreases in body weight per year were significantly lower in those who had survived than in those who had died. These results suggest that long-term hemodialysis survivors are characterized by (i) initiation of hemodialysis at a young age (ii) being free of diabetes mellitus (iii) a well-controlled cardiothoracic ratio (iv) small successive change in body weight, and (v) being free of hypercholesterolemia and hypertriglyceridemia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1744-9987
pubmed:author
pubmed:copyrightInfo
© 2010 The Authors. Journal compilation © 2010 International Society for Apheresis.
pubmed:issnType
Electronic
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
547-51
pubmed:meshHeading
pubmed-meshheading:21118361-Adolescent, pubmed-meshheading:21118361-Adult, pubmed-meshheading:21118361-Age Factors, pubmed-meshheading:21118361-Body Weight, pubmed-meshheading:21118361-Child, pubmed-meshheading:21118361-Child, Preschool, pubmed-meshheading:21118361-Diabetes Mellitus, pubmed-meshheading:21118361-Female, pubmed-meshheading:21118361-Humans, pubmed-meshheading:21118361-Hypercholesterolemia, pubmed-meshheading:21118361-Hypertriglyceridemia, pubmed-meshheading:21118361-Infant, pubmed-meshheading:21118361-Kidney Failure, Chronic, pubmed-meshheading:21118361-Male, pubmed-meshheading:21118361-Middle Aged, pubmed-meshheading:21118361-Renal Dialysis, pubmed-meshheading:21118361-Risk Factors, pubmed-meshheading:21118361-Survival Analysis, pubmed-meshheading:21118361-Survivors, pubmed-meshheading:21118361-Time Factors, pubmed-meshheading:21118361-Young Adult
pubmed:year
2010
pubmed:articleTitle
Characteristics of 20-year survivors undergoing maintenance hemodialysis.
pubmed:affiliation
Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan. morimots@hirakata.kmu.ac.jp
pubmed:publicationType
Journal Article