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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-12-1
pubmed:abstractText
Multiple evanescent white dot syndrome (MEWDS) is part of a spectrum of disease entities known as acute zonal occult outer retinopathy-complex that share photoreceptor disruption as a cardinal feature. Optical coherence tomography (OCT) allows for qualitative assessment of the integrity of the photoreceptor layer via examination of the junction between the photoreceptor inner and outer segments. A patient with atypical MEWDS who demonstrated disruption of the inner segment/outer segment junction during the acute phase of the disease is described. The change in photoreceptor architecture and abnormalities on fundus autofluorescence imaging and microperimetry were restored to normal following resolution of the disease. Using a novel OCT-based method of quantitatively measuring photoreceptor outer segment length, the authors show that photoreceptor outer segment length appears decreased acutely with restoration to normal following disease resolution. OCT can assess photoreceptor recovery, both qualitatively and quantitatively, in patients with MEWDS features.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1938-2375
pubmed:author
pubmed:copyrightInfo
Copyright 2010, SLACK Incorporated.
pubmed:issnType
Electronic
pubmed:volume
41 Suppl
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S77-80
pubmed:meshHeading
pubmed:articleTitle
Quantitative assessment of photoreceptor recovery in atypical multiple evanescent white dot syndrome.
pubmed:affiliation
Division of Epidemiology and Clinical Research, National Eye Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.
pubmed:publicationType
Journal Article, Case Reports, Research Support, N.I.H., Intramural