Source:http://linkedlifedata.com/resource/pubmed/id/21113206
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-11-29
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pubmed:abstractText |
We determined the transcript content of three genes involved in the metabolism of glucocorticoids (GC) in bovine in vitro fertilized embryos (2-blastomere stage until hatched blastocyst), trophoblast as well as the oviduct (Day 2-4 of the estrous cycle) and endometrium (Day 16 of the cycle and pregnancy). Since mRNA expression of the glucocorticoid receptor and two enzymes responsible for GC production (11?-HSD1 and 2) was demonstrated in the embryos in all pre-implantation stages as well as in the endometrium and oviduct, it is suggested that GC may serve as auto-/paracrine factors in the development of bovine pre-implantation embryos.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1642-431X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
249-56
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pubmed:meshHeading |
pubmed-meshheading:21113206-Animals,
pubmed-meshheading:21113206-Autocrine Communication,
pubmed-meshheading:21113206-Cattle,
pubmed-meshheading:21113206-Embryo Implantation,
pubmed-meshheading:21113206-Endometrium,
pubmed-meshheading:21113206-Female,
pubmed-meshheading:21113206-Glucocorticoids,
pubmed-meshheading:21113206-Oviducts,
pubmed-meshheading:21113206-Paracrine Communication,
pubmed-meshheading:21113206-Receptors, Glucocorticoid,
pubmed-meshheading:21113206-Trophoblasts
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pubmed:year |
2010
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pubmed:articleTitle |
Are glucocorticoids auto- and/or paracrine factors in early bovine embryo development and implantation?
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pubmed:affiliation |
Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Olsztyn, Poland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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