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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1978-12-2
|
| pubmed:abstractText |
Polymorphonuclear leukocytes collected from healthy human volunteers were treated with puromycin which inhibited protein synthesis in the cell. The neutrophils exhibited a marked decrease in phagocytosis after 1 h. The myeloperoxidase mediated conversion of iodide to a protein-bound form was also decreased. Hexosemonophosphate shunt activity remained similar for both puromycin treated PMN and control cells at 1 h. The results suggest that new protein synthesis is necessary to maintain PMN function at full capacity.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0301-472X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
585-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:211044-Glucose,
pubmed-meshheading:211044-Humans,
pubmed-meshheading:211044-Iodine,
pubmed-meshheading:211044-Neutrophils,
pubmed-meshheading:211044-Oxidation-Reduction,
pubmed-meshheading:211044-Peroxidase,
pubmed-meshheading:211044-Phagocytosis,
pubmed-meshheading:211044-Protein Biosynthesis,
pubmed-meshheading:211044-Puromycin,
pubmed-meshheading:211044-Staphylococcus,
pubmed-meshheading:211044-Time Factors
|
| pubmed:year |
1978
|
| pubmed:articleTitle |
The role of protein synthesis in polymorphonuclear leukocyte phagocytosis II.
|
| pubmed:publicationType |
Journal Article
|