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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2-3
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pubmed:dateCreated |
2011-2-2
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pubmed:abstractText |
The majority of psychoactive compounds, including antidepressants in clinical practice, were discovered largely by serendipity. The underlying neuropharmacological mechanisms of action of these compounds leading to resolution of depressive symptomatology are targets of the current research. Pharmacological magnetic resonance imaging (phMRI), a rapidly developing advancement of blood oxygenation level dependent (BOLD) contrast offers the potential to localize the regional sites of action in the CNS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1432-2072
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
213
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
521-31
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pubmed:meshHeading |
pubmed-meshheading:21103865-Animals,
pubmed-meshheading:21103865-Brain,
pubmed-meshheading:21103865-Citalopram,
pubmed-meshheading:21103865-Dose-Response Relationship, Drug,
pubmed-meshheading:21103865-Drug Administration Schedule,
pubmed-meshheading:21103865-Magnetic Resonance Imaging,
pubmed-meshheading:21103865-Male,
pubmed-meshheading:21103865-Oxygen,
pubmed-meshheading:21103865-Piperazines,
pubmed-meshheading:21103865-Pyridines,
pubmed-meshheading:21103865-Rats,
pubmed-meshheading:21103865-Receptors, Serotonin,
pubmed-meshheading:21103865-Serotonin,
pubmed-meshheading:21103865-Serotonin Uptake Inhibitors,
pubmed-meshheading:21103865-Time Factors
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pubmed:year |
2011
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pubmed:articleTitle |
Neuroadaptive responses to citalopram in rats using pharmacological magnetic resonance imaging.
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pubmed:affiliation |
Psychobiology Research Group, Institute of Neuroscience, Newcastle upon Tyne, UK.
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pubmed:publicationType |
Journal Article
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