Linked Life Data

21096864

Source:http://linkedlifedata.com/resource/pubmed/id/21096864

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-11-24
pubmed:abstractText
The objective of this work was to investigate the effect of sustained release of rhBMP-2, grafted to biodegradable nanoparticles (NPs) based on osteogenic differentiation of bone mesenchymal stem (BMS) cells. The release kinetics of rhBM-2 was linear with incubation time in the first two weeks. rhBMP-2 grafted NPs were as effective in inducing mineralization as the rhBMP-2 directly added to the culture media. rhBMP-2 grafted NPs had much higher expression of osteogenic markers osteopontin (OP) and osteocalcin (OC), compared to the protein directly added to culture media.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
2010
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3733-5
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Effect of sustained release of bone morphogenetic protein on osteogenic expression of mesenchymal stem cells.
pubmed:affiliation
Univ. of South Carolina, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural