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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-11-24
pubmed:abstractText
Baroreflex regulates arterial pressure by modulating ventricular and vascular properties. We investigated if the framework of circulatory equilibrium that we developed previously (Am J Physiol 2004, 2005) by extending the classic Guyton's framework is capable of predicting baroreflex induced changes in arterial pressure. In animal experiments, we estimated open loop transfer functions of baroreflexly modulated ventricular and vascular properties, synthesized baroreflex induced dynamic changes in arterial pressure using the estimated transfer functions and compared the predicted responses with measured responses. We demonstrated that the predicted baroreflex induced changes in arterial pressure matched reasonable well with those measured. We conclude that the framework of circulatory equilibrium is generalizable under the condition where baroreflex dynamically changes arterial pressure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
2010
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2869-71
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
How to quantitatively synthesize dynamic changes in arterial pressure from baroreflexly modulated ventricular and arterial properties.
pubmed:affiliation
Kyushu university, Fukuoka 8128582 Japan. tsaka@cardiol.med.kyushu-u.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't