Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-1-3
pubmed:abstractText
Environmental factors are involved to various degrees in psychiatric diseases. Unfortunately, early-life manipulations have been rarely investigated in mice. Interestingly, given the advances in genetics, combination of environmental and genetic factors to get construct validity is now possible. Herein, spontaneous activity, anxiety-like behaviour, social behaviour and short term spatial working memory were assessed in mice after maternal separation or social isolation. Of note, social withdrawal was observed in both models suggesting that this aspect needs to be better considered in future studies, particularly in testing new treatments for schizophrenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1872-7972
pubmed:author
pubmed:copyrightInfo
Crown Copyright © 2010. Published by Elsevier Ireland Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
20
pubmed:volume
488
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-4
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Effect of pre- versus post-weaning environmental disturbances on social behaviour in mice.
pubmed:affiliation
GMPc, Groupe Mémoire et Plasticité comportementale, Université de Caen Basse-Normandie, 5, rue Vaubénard, 14032 Caen cedex, France. valentine.bouet@unicaen.fr
pubmed:publicationType
Journal Article