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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-12-14
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pubmed:abstractText |
Conflicting data exist regarding the prognostic and predictive impact of survivin (BIRC5) in breast cancer. We previously reported survivin cytoplasmic-to-nuclear ratio (CNR) as an independent prognostic indicator in breast cancer. Here, we validate survivin CNR in a separate and extended cohort. Furthermore, we present new data suggesting that a low CNR may predict outcome in tamoxifen-treated patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BIRC5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Estrogen Receptor Modulators,
http://linkedlifedata.com/resource/pubmed/chemical/HER2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Inhibitor of Apoptosis Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Ki-67 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Microtubule-Associated Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Estrogen,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Progesterone,
http://linkedlifedata.com/resource/pubmed/chemical/Tamoxifen,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
639
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21092276-Adult,
pubmed-meshheading:21092276-Aged,
pubmed-meshheading:21092276-Aged, 80 and over,
pubmed-meshheading:21092276-Algorithms,
pubmed-meshheading:21092276-Breast Neoplasms,
pubmed-meshheading:21092276-Cell Nucleus,
pubmed-meshheading:21092276-Chi-Square Distribution,
pubmed-meshheading:21092276-Cytoplasm,
pubmed-meshheading:21092276-Decision Trees,
pubmed-meshheading:21092276-Estrogen Receptor Modulators,
pubmed-meshheading:21092276-Female,
pubmed-meshheading:21092276-Humans,
pubmed-meshheading:21092276-Image Interpretation, Computer-Assisted,
pubmed-meshheading:21092276-Immunohistochemistry,
pubmed-meshheading:21092276-Inhibitor of Apoptosis Proteins,
pubmed-meshheading:21092276-Kaplan-Meier Estimate,
pubmed-meshheading:21092276-Ki-67 Antigen,
pubmed-meshheading:21092276-Microtubule-Associated Proteins,
pubmed-meshheading:21092276-Middle Aged,
pubmed-meshheading:21092276-Pattern Recognition, Automated,
pubmed-meshheading:21092276-Predictive Value of Tests,
pubmed-meshheading:21092276-Proportional Hazards Models,
pubmed-meshheading:21092276-Receptor, erbB-2,
pubmed-meshheading:21092276-Receptors, Estrogen,
pubmed-meshheading:21092276-Receptors, Progesterone,
pubmed-meshheading:21092276-Reproducibility of Results,
pubmed-meshheading:21092276-Risk Assessment,
pubmed-meshheading:21092276-Risk Factors,
pubmed-meshheading:21092276-Sweden,
pubmed-meshheading:21092276-Tamoxifen,
pubmed-meshheading:21092276-Time Factors,
pubmed-meshheading:21092276-Tissue Array Analysis,
pubmed-meshheading:21092276-Treatment Outcome,
pubmed-meshheading:21092276-Tumor Markers, Biological
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pubmed:year |
2010
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pubmed:articleTitle |
Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer.
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pubmed:affiliation |
UCD Conway Institute, University College Dublin, Belfield, Ireland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Validation Studies
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