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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-1-10
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pubmed:abstractText |
Atherosclerosis is widely accepted as an inflammatory disease involving both innate and adaptive immunity. B cells and/or antibodies have previously been shown to play a protective role against atherosclerosis. Aside from their ability to bind to antigens, antibodies can influence inflammatory responses by interacting with various Fc? receptors on the surface of antigen presenting cells. Although studies in mice have determined that stimulatory Fc? receptors contribute to atherosclerosis, the role of the inhibitory Fc? receptor IIb (Fc?RIIb) has only recently been investigated.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1879-1484
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
214
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
73-80
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pubmed:meshHeading |
pubmed-meshheading:21084088-Animals,
pubmed-meshheading:21084088-Antigen-Presenting Cells,
pubmed-meshheading:21084088-Antigens,
pubmed-meshheading:21084088-Aorta,
pubmed-meshheading:21084088-Apolipoproteins E,
pubmed-meshheading:21084088-Atherosclerosis,
pubmed-meshheading:21084088-B-Lymphocytes,
pubmed-meshheading:21084088-Cytokines,
pubmed-meshheading:21084088-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:21084088-Inflammation,
pubmed-meshheading:21084088-Lipoproteins, LDL,
pubmed-meshheading:21084088-Male,
pubmed-meshheading:21084088-Mice,
pubmed-meshheading:21084088-Mice, Transgenic,
pubmed-meshheading:21084088-Receptors, IgG
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pubmed:year |
2011
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pubmed:articleTitle |
The inhibitory Fc?RIIb modulates the inflammatory response and influences atherosclerosis in male apoE(-/-) mice.
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pubmed:affiliation |
Department of Medicine, Vanderbilt University Medical Center, Nashville, USA. yanice.mendez@vanderbilt.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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