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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-11-24
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pubmed:abstractText |
The renin-angiotensin system (RAS) mediates proapoptotic, profibrotic, and proinflammatory processes in maladaptive conditions. Activation after myocardial infarction may initialize and promote cardiac remodeling. Using a novel positron-emitting ligand, we sought to determine the presence and time course of regional myocardial upregulation of the angiotensin II type 1 receptor (AT1R) and the blocking efficacy of various anti-RAS agents.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II Type 1 Receptor...,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin-Converting Enzyme...,
http://linkedlifedata.com/resource/pubmed/chemical/Enalapril,
http://linkedlifedata.com/resource/pubmed/chemical/KR 31080,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 1,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Valine,
http://linkedlifedata.com/resource/pubmed/chemical/valsartan
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1535-5667
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1956-61
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pubmed:meshHeading |
pubmed-meshheading:21078800-Angiotensin II,
pubmed-meshheading:21078800-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:21078800-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:21078800-Animals,
pubmed-meshheading:21078800-Autoradiography,
pubmed-meshheading:21078800-Enalapril,
pubmed-meshheading:21078800-Feasibility Studies,
pubmed-meshheading:21078800-Male,
pubmed-meshheading:21078800-Myocardial Reperfusion Injury,
pubmed-meshheading:21078800-Myocardium,
pubmed-meshheading:21078800-Positron-Emission Tomography,
pubmed-meshheading:21078800-Pyridines,
pubmed-meshheading:21078800-Radiopharmaceuticals,
pubmed-meshheading:21078800-Rats,
pubmed-meshheading:21078800-Rats, Wistar,
pubmed-meshheading:21078800-Receptor, Angiotensin, Type 1,
pubmed-meshheading:21078800-Renin-Angiotensin System,
pubmed-meshheading:21078800-Tetrazoles,
pubmed-meshheading:21078800-Tissue Distribution,
pubmed-meshheading:21078800-Valine
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pubmed:year |
2010
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pubmed:articleTitle |
Radionuclide imaging of angiotensin II type 1 receptor upregulation after myocardial ischemia-reperfusion injury.
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pubmed:affiliation |
Division of Nuclear Medicine, Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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