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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-3-31
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pubmed:abstractText |
Lipoprotein(a) [Lp(a)] is an established risk factor for coronary disease and stroke, but mechanisms underlying this association are unknown. We examined the association of Lp(a) with early atherosclerosis by using conventional epidemiologic analysis and a Mendelian randomization analysis. The latter utilized genetic variants that are associated with Lp(a) to estimate causal effect.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1464-3685
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
470-8
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pubmed:dateRevised |
2011-7-28
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pubmed:meshHeading |
pubmed-meshheading:21078622-Adolescent,
pubmed-meshheading:21078622-Adult,
pubmed-meshheading:21078622-Atherosclerosis,
pubmed-meshheading:21078622-Carotid Arteries,
pubmed-meshheading:21078622-Disease Progression,
pubmed-meshheading:21078622-Female,
pubmed-meshheading:21078622-Finland,
pubmed-meshheading:21078622-Genome-Wide Association Study,
pubmed-meshheading:21078622-Genomic Structural Variation,
pubmed-meshheading:21078622-Humans,
pubmed-meshheading:21078622-Lipoprotein(a),
pubmed-meshheading:21078622-Male,
pubmed-meshheading:21078622-Mendelian Randomization Analysis,
pubmed-meshheading:21078622-Prospective Studies,
pubmed-meshheading:21078622-Risk Factors
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pubmed:year |
2011
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pubmed:articleTitle |
Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study.
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pubmed:affiliation |
Department of Epidemiology, University College London, London, UK. m.kivimaki@ucl.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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