Linked Life Data

21077834

Source:http://linkedlifedata.com/resource/pubmed/id/21077834

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2010-11-16
pubmed:abstractText
A modified method of proteome comparative analysis based on preliminary removal of cell structural proteins by extraction using salt buffer and subsequent separation of extracts by two-dimensional gel electrophoresis was developed. Identification of differentially expressed proteins by mass spectrometry has revealed three proteins with noticeably increased level of synthesis in most samples of papillary thyroid tumors compared to normal tissues. An increase in ubiquitin content was found for the first time. Oncomarker search efficiencies by two-dimensional gel electrophoresis and bioinformatic search were compared.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1608-3040
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1148-52
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Identification of proteins overexpressed in papillary thyroid tumors.
pubmed:affiliation
Clinical Research Center PreMed, Moscow, 121357, Russia. larsipina@rambler.ru
pubmed:publicationType
Journal Article