| pubmed-article:21075627 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21075627 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:21075627 | lifeskim:mentions | umls-concept:C0031330 | lld:lifeskim |
| pubmed-article:21075627 | lifeskim:mentions | umls-concept:C0024117 | lld:lifeskim |
| pubmed-article:21075627 | lifeskim:mentions | umls-concept:C0243192 | lld:lifeskim |
| pubmed-article:21075627 | lifeskim:mentions | umls-concept:C0004048 | lld:lifeskim |
| pubmed-article:21075627 | lifeskim:mentions | umls-concept:C0243076 | lld:lifeskim |
| pubmed-article:21075627 | lifeskim:mentions | umls-concept:C1554184 | lld:lifeskim |
| pubmed-article:21075627 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
| pubmed-article:21075627 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:21075627 | pubmed:dateCreated | 2011-4-25 | lld:pubmed |
| pubmed-article:21075627 | pubmed:abstractText | This paper describes the successful design and development of dual pharmacology ?-2 agonists-M3 antagonists, for the treatment of chronic obstructive pulmonary disorder using the principles of 'inhalation by design'. A key feature of this work is the combination of balanced potency and pharmacodynamic duration with desirable pharmacokinetic and material properties, whilst keeping synthetic complexity to a minimum. | lld:pubmed |
| pubmed-article:21075627 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21075627 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075627 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21075627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075627 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21075627 | pubmed:month | May | lld:pubmed |
| pubmed-article:21075627 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:FluxWW | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:JamraM AMA | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:FeederNeilN | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:PriceDavid... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:NewmanSandra... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:BunnageMark... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:OsborneRachel... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:TrevethickMic... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:FairmanDavidD | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:ClarkeNickN | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:SelbyMatthew... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:PatelSheenaS | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:MarshallStuar... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:JonesRhys MRM | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:WrightKaren... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:StuartEmilio... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:BaldockHelenH | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:BurrowsJaneJ | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:CoghlanMichel... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:EntwistleDavi... | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:FultonCraigC | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:HiltonLauraL | lld:pubmed |
| pubmed-article:21075627 | pubmed:author | pubmed-author:KenyonAmy SAS | lld:pubmed |
| pubmed-article:21075627 | pubmed:copyrightInfo | Copyright © 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:21075627 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21075627 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:21075627 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:21075627 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21075627 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21075627 | pubmed:pagination | 2759-63 | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:meshHeading | pubmed-meshheading:21075627... | lld:pubmed |
| pubmed-article:21075627 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21075627 | pubmed:articleTitle | Inhalation by design: dual pharmacology ?-2 agonists/M3 antagonists for the treatment of COPD. | lld:pubmed |
| pubmed-article:21075627 | pubmed:affiliation | Sandwich Chemistry, World Wide Medicinal Chemistry, Pfizer, Ramsgate Road, Sandwich CT13 9NJ, UK. lyn.jones@pfizer.com | lld:pubmed |
| pubmed-article:21075627 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:21075627 | lld:chembl |
