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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-12-27
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pubmed:abstractText |
Blockade of T cell costimulatory molecules represents a promising new method of attenuating donor-reactive T cell responses to promote graft survival following transplantation. However, recent studies in murine models have shown the presence of an initial high frequency of naïve donor-reactive T cells may render this strategy ineffective.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1878-5492
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
94-9
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:21073953-Animals,
pubmed-meshheading:21073953-Antibodies, Monoclonal,
pubmed-meshheading:21073953-Antigens, CD28,
pubmed-meshheading:21073953-Cell Division,
pubmed-meshheading:21073953-Flow Cytometry,
pubmed-meshheading:21073953-Gene Expression Regulation,
pubmed-meshheading:21073953-Graft Survival,
pubmed-meshheading:21073953-Immunoconjugates,
pubmed-meshheading:21073953-Interleukin-2,
pubmed-meshheading:21073953-Interleukin-2 Receptor alpha Subunit,
pubmed-meshheading:21073953-Mice,
pubmed-meshheading:21073953-Mice, Transgenic,
pubmed-meshheading:21073953-Signal Transduction,
pubmed-meshheading:21073953-T-Lymphocytes
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pubmed:year |
2011
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pubmed:articleTitle |
CD28 blockade induces division-dependent downregulation of interleukin-2 receptor alpha.
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pubmed:affiliation |
Emory Transplant Center and Department of Surgery, Emory University, Atlanta, GA 30079, United States. mandy.ford@emory.edu
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pubmed:publicationType |
Journal Article
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