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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-4-28
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pubmed:abstractText |
Platelets contain an array of biologic mediators that can modulate inflammation and repair processes including proinflammatory mediators and growth factors. Previous studies have shown that periodontitis and periodontal repair are associated with platelet activation. We hypothesized that drug-induced platelet inactivation may interfere in the processes of inflammation and repair in experimental periodontitis in rats by suppressing the release of biologic mediators from platelets to the site of injury.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1943-3670
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
767-77
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pubmed:meshHeading |
pubmed-meshheading:21073332-Alveolar Bone Loss,
pubmed-meshheading:21073332-Animals,
pubmed-meshheading:21073332-Aspirin,
pubmed-meshheading:21073332-Blood Platelets,
pubmed-meshheading:21073332-Bone Density,
pubmed-meshheading:21073332-Bone Regeneration,
pubmed-meshheading:21073332-Inflammation Mediators,
pubmed-meshheading:21073332-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:21073332-Interleukin-6,
pubmed-meshheading:21073332-Leukocytes,
pubmed-meshheading:21073332-Male,
pubmed-meshheading:21073332-Mandibular Diseases,
pubmed-meshheading:21073332-Periodontal Attachment Loss,
pubmed-meshheading:21073332-Periodontitis,
pubmed-meshheading:21073332-Periodontium,
pubmed-meshheading:21073332-Platelet Activation,
pubmed-meshheading:21073332-Platelet Aggregation Inhibitors,
pubmed-meshheading:21073332-Random Allocation,
pubmed-meshheading:21073332-Rats,
pubmed-meshheading:21073332-Rats, Sprague-Dawley,
pubmed-meshheading:21073332-Thromboxane A2,
pubmed-meshheading:21073332-Ticlopidine,
pubmed-meshheading:21073332-Time Factors,
pubmed-meshheading:21073332-Tumor Necrosis Factor-alpha,
pubmed-meshheading:21073332-Wound Healing,
pubmed-meshheading:21073332-X-Ray Microtomography
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pubmed:year |
2011
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pubmed:articleTitle |
Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats.
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pubmed:affiliation |
Department of Physiology and Pathology, Faculdade de Odontologia de Araraquara, UNESP, Universidade Estadual Paulista, Araraquara, SP, Brazil.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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